Pfizer is one of Ireland’s leading employers and the largest pharmaceutical sector investor and employer. Pfizer employs over 4,000 colleagues across eight locations in Cork, Dublin, Kildare and Limerick.
Pfizer in Ireland
Pfizer Ireland Pharmaceuticals’ Grange Castle manufacturing plant is situated on a 90-acre site at the Grange Castle Business Park in Clondalkin, South County Dublin. Grange Castle’s state-of-the-art technology, cutting edge thinking and production expertise result in the production of quality-driven products that improve people’s lives around the world. The site manufactures a number of products for the prevention or treatment of serious illnesses such including rheumatoid arthritis and pneumococcal disease in young children. Over 1,000 full-time employees work at Grange Castle.
Some 100,000 people in Ireland are known to be suffering with arthritis and many more are claimed to be undiagnosed. This lesson looks at the impact of arthritis on skeletal joints. The various types of the disease are described — osteoarthritis, rheumatoid arthritis, fibromyalgia, gout, lupus and ankylosing spondylitis.
This lesson describes the modern drug discovery process. It begins with understanding the underlying cause of disease and then identifying drug candidates that target specific cellular pathways involved in the disease process.
The immune system is critical to our ability to resist disease. This lesson deals with the topic of vaccines. It relates how vaccines are evolving and describes different types of vaccine. Some first and second generation vaccines are identified. The lesson describes how third generation vaccines are still at an experimental stage.
This lesson deals with developments in cell culture and its applications. The basics of cell division are summarised and the process by which cells divide a limited number of times is outlined. The lesson also explains what is meant by stem cells, embryonic stem cells, cell lines and cell banking.
This lesson describes six experiments that demonstrate the effects of temperature, concentration etc. on the action of catalase, an enzyme that decomposes hydrogen peroxide.
Some aspects of volumetric analysis are discussed in this lesson. The common methods of expressing concentration are explained and there are worked examples of how to calculate concentration.
The human defence system is the subject of this lesson. The general and specific defence systems are covered. The attributes of the immune system are described. The response of the body to an antigen-antibody complex is also explained.